Mayne Preceptory was a medieval house of Knights Hospitaller in Dorset, England, which caused the name of the settlement to change from Domesday-era Maine (one of two named Maine in Cullifordtree Hundred) to Friar Mayne by the mid 14th century. The preceptory was established between 1290 and 1338. It declined in activity until 1533, where it began leasing its bailiwick to provide stipends for rectories, vicarages and the larger preceptories in other locations.