Metkefamide
Metkefamide (INN; LY-127,623), or metkephamid acetate (USAN), but most frequently referred to simply as metkephamid, is a synthetic opioid pentapeptide and derivative of [Met]enkephalin with the amino acid sequence Tyr-D-Ala-Gly-Phe-(N-Me)-Met-NH2. It behaves as a potent agonist of the δ- and μ-opioid receptors with roughly equipotent affinity, and also has similarly high affinity as well as subtype-selectivity for the κ3-opioid receptor.
primaryTopic
Metkefamide
Metkefamide (INN; LY-127,623), or metkephamid acetate (USAN), but most frequently referred to simply as metkephamid, is a synthetic opioid pentapeptide and derivative of [Met]enkephalin with the amino acid sequence Tyr-D-Ala-Gly-Phe-(N-Me)-Met-NH2. It behaves as a potent agonist of the δ- and μ-opioid receptors with roughly equipotent affinity, and also has similarly high affinity as well as subtype-selectivity for the κ3-opioid receptor.
has abstract
Metkefamide (INN; LY-127,623), ...... hed the pharmaceutical market.
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Bioavailability
CAS number
66960-34-7
66960-35-8 (acetate)
FDA UNII code
MNL20FXH9Y
PubChem
Wikipage page ID
35,641,157
page length (characters) of wiki page
Wikipage revision ID
1,001,445,443
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ATC prefix
None
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bioavailability
CAS number
CAS supplemental
ChemSpiderID
elimination half-life
IUPAC name
(L)-tyrosyl-(D)-alanylglycyl-(L)-phenylalanyl-N2-methyl-(L)-methioninamide
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metabolism
protein bound
PubChem
SMILES
O=C[C@@H]CCSC
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StdInChIKey
FWDIKROEWJOQIQ-JMBSJVKXSA-N
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UNII
MNL20FXH9Y
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wikiPageUsesTemplate
subject
hypernym
comment
Metkefamide (INN; LY-127,623), ...... ty for the κ3-opioid receptor.
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label
Metkefamide
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