Mr. One-Two-Three Part 2 (retroactively titled Mister One-Two-Three Strikes Again) is a 1981 Filipino comedy film written and directed by Mike Relon Makiling and starring the comedy trio Tito Sotto, Vic Sotto, and Joey de Leon. Based on the Pinoy Komiks characters created by L. P. Calixto, it is a sequel to the 1980 film Mr. One-Two-Three. The film was released in theaters by GP Films on July 31, 1981, and was later reissued in early April 1988. Critic Lav Diaz criticized the film as simplistically comical and cliché, with its gags already done before by Filipino comedians Dolphy, Chiquito, and Cachupoy, though he noted that it demonstrates the then-current state of comedy films produced in the Philippines.