MutS-1
MutS is a mismatch DNA repair protein, originally described in Escherichia coli. Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome. It involves the correction of mismatched base pairs that have been missed by the proofreading element (Klenow fragment) of the DNA polymerase complex. The post-replicative Mismatch Repair System (MMRS) of Escherichia coli involves MutS (Mutator S), MutL and MutH proteins, and acts to correct point mutations or small insertion/deletion loops produced during DNA replication.
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MutS-1
MutS is a mismatch DNA repair protein, originally described in Escherichia coli. Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome. It involves the correction of mismatched base pairs that have been missed by the proofreading element (Klenow fragment) of the DNA polymerase complex. The post-replicative Mismatch Repair System (MMRS) of Escherichia coli involves MutS (Mutator S), MutL and MutH proteins, and acts to correct point mutations or small insertion/deletion loops produced during DNA replication.
has abstract
MutS is a mismatch DNA repair ...... is a mismatch binding protein.
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32,116,368
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994,494,951
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caption
The crystal structure of E. coli MutS binding to DNA with an a:a mismatch
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InterPro
IPR007695
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name
MutS_I
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Pfam
PF01624
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PROSITE
PDOC00388
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SMART
MUTSd
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symbol
MutS_I
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wikiPageUsesTemplate
subject
comment
MutS is a mismatch DNA repair ...... oduced during DNA replication.
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label
MutS-1
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