NKG2D
NKG2D is an activating receptor (transmembrane protein) belonging to the NKG2 family of C-type lectin-like receptors. NKG2D is encoded by KLRK1 (killer cell lectin like receptor K1) gene which is located in the NK-gene complex (NKC) situated on chromosome 6 in mice and chromosome 12 in humans. In mice, it is expressed by NK cells, NK1.1+ T cells, γδ T cells, activated CD8+ αβ T cells and activated macrophages. In humans, it is expressed by NK cells, γδ T cells and CD8+ αβ T cells. NKG2D recognizes induced-self proteins from MIC and RAET1/ULBP families which appear on the surface of stressed, malignant transformed, and infected cells.
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C-type lectinCD94/NKG2CGAS–STING cytosolic DNA sensing pathwayCLEC1BCellular senescenceCytokine-induced killer cellGluten immunochemistryH60 familyHuman betaherpesvirus 5ImmunoevasinIndex of immunology articlesInduced-self antigenInnate lymphoid cellInterleukin 10KLRK1Killer activation receptorList of human clusters of differentiationList of human protein-coding genes 2MHC class I polypeptide–related sequence AMHC class I polypeptide–related sequence BMucosal associated invariant T cellMurine UL16 binding protein-like transcriptNKG2Natural killer cellOutline of immunologyRAET1ERAET1GRAET1LRae-1 familyULBP1ULBP2ULBP3XMEN disease
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NKG2D
NKG2D is an activating receptor (transmembrane protein) belonging to the NKG2 family of C-type lectin-like receptors. NKG2D is encoded by KLRK1 (killer cell lectin like receptor K1) gene which is located in the NK-gene complex (NKC) situated on chromosome 6 in mice and chromosome 12 in humans. In mice, it is expressed by NK cells, NK1.1+ T cells, γδ T cells, activated CD8+ αβ T cells and activated macrophages. In humans, it is expressed by NK cells, γδ T cells and CD8+ αβ T cells. NKG2D recognizes induced-self proteins from MIC and RAET1/ULBP families which appear on the surface of stressed, malignant transformed, and infected cells.
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NKG2D is an activating recepto ...... ansformed, and infected cells.
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NKG2D is an activating recepto ...... ansformed, and infected cells.
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NKG2D
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