The Nathan Lester House is a historic house museum at 153 Vinegar Hill Road in the Gales Ferry section of Ledyard, Connecticut. Built in 1793, it is a well-preserved example of an unpretentious late 18th-century farmhouse, and one of the few houses of that age left in the town. It is located on over 136 acres (55 ha) of land, now owned by the town, which serves as a park and conservation land with trails. Is listed on the National Register of Historic Places in 1972.