This list presents the full set of buildings, structures, objects, sites, or districts designated on the National Register of Historic Places in Northwest Portland, Oregon, and offers brief descriptive information about each of them. The National Register recognizes places of national, state, or local historic significance across the United States. Out of over 90,000 National Register sites nationwide, Oregon is home to over 2,000, and over one-fourth of those are found partially or wholly in Portland. While these sites are widely spread across all six of Portland's quadrants, heavy concentrations are found in the Downtown and Southwest Hills neighborhoods of the Southwest quadrant, and the Northwest District neighborhood of the Northwest quadrant.