New York State Route 349 (NY 349) is an east–west state highway in Fulton County, New York, in the United States. The highway extends for 3.58 miles (5.76 km) across largely rural terrain from an intersection with NY 30A in the town of Johnstown to a junction with NY 30 in the town of Mayfield. The westernmost section of the route is known as East State Street Extension. NY 349 was assigned c. 1931 to the portion of its alignment between County Route 154 (CR 154; then ) and NY 30. It was extended west to its present terminus in the mid-1950s after NY 148 was rerouted onto an arterial highway between Gloversville and Mayfield.