The Niagara Apothecary was an apothecary in Niagara-on-the-Lake, Ontario, established no later than 1820, and is now a National Historic Site of Canada. It was operated by a series of successive owners, most of whom had apprenticed under the preceding owner. In the 1960s, it was purchased by the Niagara Foundation, which targeted the building and its contents for preservation. It was purchased by the provincially-owned Ontario Heritage Foundation in 1969, which undertook a preservation effort culminating in May 1971, when the property was re-opened as a museum.