Olga Guramishvili-Nikoladze (Georgian: ოლღა გურამიშვილი-ნიკოლაძე, 29 July 1855 – 24 May 1940) was a Georgian biologist and educator. One of the first women to study abroad, she earned a degree in pedagogy and brought advanced teaching methods to Georgia. In 1886, she founded a girls' school, and later a women's gymnasium, in Didi Jikhaishi. At the school, she introduced sericulture to the country and taught her students mechanical knitting and weaving. In her later career, she served as the chair of the school board in Poti from 1894 to 1912. She is remembered for her contributions to education and a street in Tbilisi bears her name.