Original antigenic sin
Original antigenic sin, also known as antigenic imprinting or the Hoskins effect, refers to the propensity of the body's immune system to preferentially utilize immunological memory based on a previous infection when a second slightly different version of that foreign pathogen (e.g. a virus or bacterium) is encountered. This leaves the immune system "trapped" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections. Antibodies or T-cells induced during infections with the first variant of the pathogen are subject to a form of original antigenic sin, termed repertoire freeze.
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Original antigenic sin
Original antigenic sin, also known as antigenic imprinting or the Hoskins effect, refers to the propensity of the body's immune system to preferentially utilize immunological memory based on a previous infection when a second slightly different version of that foreign pathogen (e.g. a virus or bacterium) is encountered. This leaves the immune system "trapped" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections. Antibodies or T-cells induced during infections with the first variant of the pathogen are subject to a form of original antigenic sin, termed repertoire freeze.
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Die Antigenerbsünde (englisch: ...... nte des Virus vorhanden waren.
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El pecado original antigénico ...... teológico del pecado original.
@es
Il peccato originale antigenic ...... f the Original Antigenic Sin."
@it
Le péché originel antigénique, ...... antigène légèrement différent.
@fr
Original antigenic sin, also k ...... f the Original Antigenic Sin."
@en
Антигенный импринтинг (англ. O ...... аботу А. С. Горбуновой (1966).
@ru
抗原原罪(英文：original antigenic sin ...... 印會掌管隨後的抗體反應。我們稱之為抗原原罪的道理。｣(中譯)
@zh
抗原原罪（こうげんげんざい original antigen ...... なわち『抗原原罪』の単語が用いられる場合）との順で解説する。
@ja
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Die Antigenerbsünde (englisch: ...... nte des Virus vorhanden waren.
@de
El pecado original antigénico ...... a humana (HIV) y otros virus.
@es
Il peccato originale antigenic ...... diverse da quello originario.
@it
Le péché originel antigénique, ...... efficaces lors d’infections su
@fr
Original antigenic sin, also k ...... sin, termed repertoire freeze.
@en
Антигенный импринтинг (англ. O ...... организм и его реакций на них.
@ru
抗原原罪(英文：original antigenic sin ...... 印會掌管隨後的抗體反應。我們稱之為抗原原罪的道理。｣(中譯)
@zh
抗原原罪（こうげんげんざい original antigen ...... なわち『抗原原罪』の単語が用いられる場合）との順で解説する。
@ja
label
Antigenerbsünde
@de
Original antigenic sin
@en
Pecado original antigénico
@es
Peccato originale antigenico
@it
Péché originel antigénique
@fr
Антигенный импринтинг
@ru
抗原原罪
@ja
抗原原罪
@zh