The Payne Hotel is a former stagecoach inn located along Highway 33 in Saukville, Wisconsin. Deemed worthy of preservation, the hotel has been listed on the National Register of Historic Places since March 14, 1991. William Payne was born in London in 1806 and immigrated to the U.S. in 1826. In 1846 he founded Saukville, building a sawmill and gristmill on the Milwaukee River. In 1848 he built the Payne Hotel where the old Dekorra Military Road met the old Green Bay Trail. It served as a stagecoach stop for people traveling between Chicago/Milwaukee and Green Bay.