Pemoline
Pemoline is a stimulant drug of the 4-oxazolidinone class. It was first synthesized in 1913 but its activity was not discovered until the 1930s. Under the names Betanamin, Cylert, Tradon, and Ceractiv it was used as a medication to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Under the Convention on Psychotropic Substances, it is a Schedule IV drug. It is no longer generally available in the United States as a result of the Food and Drug Administration (FDA) withdrawing approval of pemoline as an indicated treatment for ADHD, due to its implication in liver failures among children who were receiving the medication. An FDA Alert warned against prescribing pemoline for ADHD. This spurred Abbott Laboratories, the patent owner of Cylert, to cease manufacturing Cylert.
ATC code N06BA05ATCvet code QN06BA05AzoksodonAzoxodonAzoxodoneBetanaminCentraminConstimolCylertCylert ChewableDantrominDeltaminDeltamineEndolinFenoxazolHytonHyton asaJuston-WirkstoffKethamedMyaminNPL 1NitanNotairOkodonPemolinPemolinaPhenalonePhenilonePioxolPomolinePondexRonylSigmadynSistralStimulStimulolTradonTradoneVolitalVolitol
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1977 Tour de France2005_World_Championships_in_Athletics4,4'-Dimethylaminorex4-MethylaminorexATC code N06ATC code N06BA05ATCvet code QN06BA05AminorexAttention deficit hyperactivity disorder managementAzoksodonAzoxodonAzoxodoneBetanaminC9H8N2O2CentraminClominorexConstimolControlled Drugs and Substances ActConvention on Psychotropic SubstancesCyclazodoneCylertCylert ChewableDantrominDarya SafonovaDecree-Law 15/93DeltaminDeltamineDmitry VlasovDopaminergicDoping at the Olympic GamesDrug policy of IndiaDrugs controlled by the German BetäubungsmittelgesetzDrugs controlled by the UK Misuse of Drugs ActDyskinesiaEddy MerckxEndolinExcessive daytime sleepinessFenoxazolFenozoloneFio
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Pemoline
Pemoline is a stimulant drug of the 4-oxazolidinone class. It was first synthesized in 1913 but its activity was not discovered until the 1930s. Under the names Betanamin, Cylert, Tradon, and Ceractiv it was used as a medication to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Under the Convention on Psychotropic Substances, it is a Schedule IV drug. It is no longer generally available in the United States as a result of the Food and Drug Administration (FDA) withdrawing approval of pemoline as an indicated treatment for ADHD, due to its implication in liver failures among children who were receiving the medication. An FDA Alert warned against prescribing pemoline for ADHD. This spurred Abbott Laboratories, the patent owner of Cylert, to cease manufacturing Cylert.
has abstract
La pemolina es un estimulante moderado del sistema nervioso central.
@es
La pemolina è un farmaco con a ...... apianto epatico od alla morte.
@it
La pémoline est une substance ...... bstances psychotropes de 1971.
@fr
Pemolin ist ein Arzneistoff mi ...... bungsmittelrechtlich geregelt.
@de
Pemolin, summaformel C9H8N2O2, ...... mt i förteckning II i Sverige.
@sv
Pemolina é um fármaco utilizad ...... ica, sonolência e narcolepsia.
@pt
Pemolina – organiczny związek ...... ch zamieszczonych w Wikipedii.
@pl
Pemoline (merknamen onder ande ...... in 1975 op de markt gebracht.
@nl
Pemoline is a stimulant drug o ...... ric equivalents followed suit.
@en
Пемолин — лекарственное средст ...... еской усталости и нарколепсии.
@ru
alternative name
Cylert
@en
Bioavailability
CAS number
ChEMBL
DrugBank
FDA UNII code
7GAQ2332NK
KEGG
PubChem
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
1,026,130,604
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ATC prefix
N06
@en
ATC suffix
BA05
@en
bioavailability
CAS number
ChEBI
ChEMBL
ChemSpiderID
chirality
DrugBank
DB01230
@en
elimination half-life
excretion
?
@en
image
@en
IUPAC name
KEGG
D00744
@en
legal AU
S4
@en
legal CA
Schedule IV
@en
legal DE
Rx-only/Anlage III
@en
legal US
Schedule IV
@en
metabolism
pregnancy US
B
@en
PubChem
routes of administration
Oral
@en
SMILES
O=C2\N=CN
@en
StdInChIKey
NRNCYVBFPDDJNE-UHFFFAOYSA-N
@en
tradename
Cylert
@en
Verifiedfields
changed
@en
verifiedrevid
461,086,403