Penicillin-binding proteins
Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just reflects the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs, which are essential for bacterial cell wall synthesis. PBPs are members of a subgroup of enzymes called transpeptidases. Specifically, PBPs are DD-transpeptidases.
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AntibioticAntibiotic resistance in gonorrheaAntimicrobial resistanceAztreonamBacterial morphological plasticityBeta-lactamBinding proteinBolA-like protein familyBordetella aviumCarbapenemCarboxypeptidaseCefalexinCefazolinCefiximeCefotiamCefovecinCeftezoleCeftriaxoneCefuroxime axetilCephalosporinCephalosporin CDD-transpeptidaseDavid PhoenixDicloxacillinDiscovery and development of cephalosporinsDrug resistanceE. coli long-term evolution experimentEagle effectErtapenemFilamentationFlucloxacillinFluorescent D-amino acidsHaemophilus influenzaeJoyoti BasuLACTBLactivicinLaura PiddockLipid IIList of MeSH codes (D08)List of MeSH codes (D12.776.097)
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Biological target
primaryTopic
Penicillin-binding proteins
Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just reflects the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs, which are essential for bacterial cell wall synthesis. PBPs are members of a subgroup of enzymes called transpeptidases. Specifically, PBPs are DD-transpeptidases.
has abstract
Białka wiążące penicylinę (ang ...... o na który działa antybiotyk).
@pl
Ein Penicillin-bindendes Protein (PBP) ist ein Protein, das Penicillin binden kann.
@de
Le proteine leganti la penicil ...... uzione della parete batterica.
@it
Penicillin-binding proteins (P ...... , PBPs are DD-transpeptidases.
@en
Пенициллин-связывающие белки ( ...... сокому сродству к пенициллину.
@ru
البنسلين ملازم البروتينات (PBP ...... الخلية البكتيري المنشأ حيوياً.
@ar
ペニシリン結合タンパク質(ペニシリンけつごうたんぱくしつ、英 ...... タム系抗生物質との結合能が低下することで発生する場合もある。
@ja
Symbol
PCN-bd_Tpept
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Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
992,239,874
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InterPro
IPR001460
@en
IPR005311
@en
Membranome superfamily
name
Penicillin-binding protein, dimerisation domain
@en
Penicillin-binding protein, transpeptidase
@en
OPM family
OPM protein
Pfam
PF00905
@en
PF03717
@en
symbol
PBP_dimer
@en
PCN-bd_Tpept
@en
wikiPageUsesTemplate
subject
comment
Białka wiążące penicylinę (ang ...... k prowadzi do śmierci komórki.
@pl
Ein Penicillin-bindendes Protein (PBP) ist ein Protein, das Penicillin binden kann.
@de
Le proteine leganti la penicil ...... per gli antibiotici di parete.
@it
Penicillin-binding proteins (P ...... , PBPs are DD-transpeptidases.
@en
Пенициллин-связывающие белки ( ...... сокому сродству к пенициллину.
@ru
البنسلين ملازم البروتينات (PBP ...... الخلية البكتيري المنشأ حيوياً.
@ar
ペニシリン結合タンパク質(ペニシリンけつごうたんぱくしつ、英 ...... タム系抗生物質との結合能が低下することで発生する場合もある。
@ja
label
Białka wiążące penicylinę
@pl
Penicillin-bindendes Protein
@de
Penicillin-binding proteins
@en
Proteine leganti la penicillina
@it
Пенициллин-связывающие белки
@ru
بروتين رابط للبنسلين
@ar
ペニシリン結合タンパク質
@ja
페니실린 결합 단백질
@ko