Pennsylvania Route 416 (PA 416) is a 17.4-mile-long (28.0 km) state highway located in Franklin County, Pennsylvania. The southern terminus is at the Maryland state line near , where the road continues into that state as Cearfoss Pike, leading to Maryland Route 58 (MD 58). The northern terminus is at U.S. Route 30 (US 30) in St. Thomas Township. PA 416 is a two-lane undivided road that runs through farmland in southwestern Franklin County. The route heads northwest from the state line and crosses PA 995 in Welsh Run before it bends northeast and reaches an intersection with PA 16. PA 416 turns northwest for a concurrency with PA 16 and heads to Mercersburg, where PA 75 joins the two routes. PA 75 and PA 416 split from PA 16 and head northeast out of Mercersburg. PA 416 splits from PA 75 an