Pesticide regulation in the United States is primarily a responsibility of the Environmental Protection Agency. In America, it was not till the 1950s that pesticides were regulated in terms of their safety. The Pesticides Control Amendment (PCA) of 1954 was the first time Congress passed guidance regarding the establishment of safe limits for pesticide residues on food. It authorized the FDA to ban pesticides they determined to be unsafe if they were sprayed directly on food. The Food Additives Amendment, which included the , prohibited the pesticide residues from any carcinogenic pesticides in processed food. In 1959, pesticides were required to be registered.