Peters Point was built by Isaac Jenkins Mikell in 1840. The house was built at the intersection of St. Pierre's Creek and Fishing Creek. The site was Gen. Lafayette’s departure point from the island in 1826 after he visited the island during a southern tour. The plantation house displays early Edisto Island plantation and Greek Revival styles. Mikell, a Princeton graduate, was one of the wealthiest planters in the state. He served as a magistrate and commissioner of the public schools of Edisto. One of Mikell's projects was the landscaping of the grounds surrounding the house. The house was listed in the National Register of Historic Places on June 19, 1973.