Phosphodiesterase 2
The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite the fact that their amino acid sequences show considerable divergence. The PDEs have different substrate specificities. Some are cAMP selective hydrolases (PDE 4, -7 and -8), others are cGMP selective hydrolases (PDE 5, -6 and -9) and the rest can hydrolyse both cAMP and cGMP (PDE1, -2, -3, -10 and -11).
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Phosphodiesterase 2
The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite the fact that their amino acid sequences show considerable divergence. The PDEs have different substrate specificities. Some are cAMP selective hydrolases (PDE 4, -7 and -8), others are cGMP selective hydrolases (PDE 5, -6 and -9) and the rest can hydrolyse both cAMP and cGMP (PDE1, -2, -3, -10 and -11).
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La fosfodiesterasa 2 HGNC PDE2 ...... ación alostérica de la enzima.
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The PDE2 (phosphodiesterase 2) ...... ces in their kinetic behavior.
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1,021,871,720
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Bay 60-7550
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EHNA
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Oxindole
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PDP
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vertical
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PDE2 inhibitors
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La fosfodiesterasa 2 HGNC PDE2 ...... mas (PDE2A3, PDE2A1 y PDE2A2).
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The PDE2 (phosphodiesterase 2) ...... P (PDE1, -2, -3, -10 and -11).
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Fosfodiesterasa 2
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Phosphodiesterase 2
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