Poillon-Seguine-Britton House was a historic home located in Great Kills, Staten Island, New York, near Great Kills Harbor. The original section was built about 1695 for the French immigrant Jacques Poillon, with a 2-story addition completed about 1845 after the home was sold to Joseph Seguine, and a final major expansion in 1930 for Richard Britton. It was a substantial, 2+1⁄2-story, stone-and-wood structure in the local vernacular style. The interior had some notable Greek Revival style details.