R-SMAD
R-SMADs are receptor-regulated SMADs. SMADs are transcription factors that transduce extracellular TGF-β superfamily ligand signaling from cell membrane bound TGF-β receptors into the nucleus where they activate transcription TGF-β target genes. R-SMADS are directly phosphorylated on their c-terminus by type 1 TGF-β receptors through their intracellular kinase domain, leading to r-SMAD activation. R-SMADS include SMAD2 and SMAD3 from the TGF-β/Activin/Nodal branch, and SMAD1, SMAD5 and SMAD8 from the BMP/GDP branch of TGF-β signaling.
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ACVR1ACVR1BACVR1CActivin and inhibinActivin type 1 receptorsActivin type 2 receptorsBMPR2Bone morphogenetic protein 4Daf-14Daf-8EID2I-SMADList of MeSH codes (D12.644)List of MeSH codes (D12.776)List of MeSH codes (D12.776.157)List of MeSH codes (D12.776.260)List of MeSH codes (D12.776.476)List of MeSH codes (D12.776.930)MECOMMothers against decapentaplegic homolog 1Mothers against decapentaplegic homolog 5Mothers against decapentaplegic homolog 9Paracrine signalingReceptor regulated SMADReceptor regulated smadsSKI proteinSMADSMAD (protein)Smad proteins, receptor-regulatedTGF beta signaling pathwayTranscription factorTransforming growth factor betaUpstream and downstream (transduction)Zinc finger FYVE domain-containing protein 9
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R-SMAD
R-SMADs are receptor-regulated SMADs. SMADs are transcription factors that transduce extracellular TGF-β superfamily ligand signaling from cell membrane bound TGF-β receptors into the nucleus where they activate transcription TGF-β target genes. R-SMADS are directly phosphorylated on their c-terminus by type 1 TGF-β receptors through their intracellular kinase domain, leading to r-SMAD activation. R-SMADS include SMAD2 and SMAD3 from the TGF-β/Activin/Nodal branch, and SMAD1, SMAD5 and SMAD8 from the BMP/GDP branch of TGF-β signaling.
has abstract
R-SMADs are receptor-regulated ...... F-β receptors for degradation.
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R-SMADs es un tipo de proteína ...... teína morfogénica ósea (BMP).
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R-SMADs are receptor-regulated ...... GDP branch of TGF-β signaling.
@en
R-SMADs es un tipo de proteína ...... teína morfogénica ósea (BMP).
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label
R-SMAD
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R-SMAD
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