SAH riboswitch
SAH riboswitches are a kind of riboswitch that bind S-adenosylhomocysteine (SAH). When the coenzyme S-adenosylmethionine (SAM) is used in a methylation reaction, SAH is produced. SAH riboswitches typically up-regulate genes involved in recycling SAH to create more SAM (or the metabolically related methionine). This is particularly relevant to cells, because high levels of SAH can be toxic. Originally identified by bioinformatics, SAH riboswitches are apparent in many species of bacteria, predominantly certain Proteobacteria and Actinobacteria. The atomic-resolution 3-dimensional structure of an SAH riboswitch has been solved using X-ray crystallography.
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SAH riboswitch
SAH riboswitches are a kind of riboswitch that bind S-adenosylhomocysteine (SAH). When the coenzyme S-adenosylmethionine (SAM) is used in a methylation reaction, SAH is produced. SAH riboswitches typically up-regulate genes involved in recycling SAH to create more SAM (or the metabolically related methionine). This is particularly relevant to cells, because high levels of SAH can be toxic. Originally identified by bioinformatics, SAH riboswitches are apparent in many species of bacteria, predominantly certain Proteobacteria and Actinobacteria. The atomic-resolution 3-dimensional structure of an SAH riboswitch has been solved using X-ray crystallography.
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SAH riboswitches are a kind of ...... d using X-ray crystallography.
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16,716,752
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994,774,528
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Predicted secondary structure and sequence conservation of SAH_riboswitch
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id
RF01057
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name
S-adenosyl-L-homocysteine riboswitch
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SAH_riboswitch
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Rfam
RF01057
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RNA type
symbol
SAH_riboswitch
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Tax domain
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SAH riboswitches are a kind of ...... d using X-ray crystallography.
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label
SAH riboswitch
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