The Saint-Jean River (French: Rivière Saint-Jean) is a major tributary of the north shore of the Gulf of St. Lawrence, flowing in the unorganized territory of Lac-Jérôme and in the municipality of Rivière-Saint-Jean, in the Minganie Regional County Municipality, in the administrative region of Côte-Nord, in the province of Quebec (Canada). It is considered one of the three salmon rivers on the North Shore. The "Saint John River" gives its name to the municipality of Rivière-Saint-Jean.