Samuel Moore (February 8, 1774 – February 18, 1861) was a member of the U.S. House of Representatives from Pennsylvania. Samuel Moore was born in Deerfield (now Deerfield Street) in the Province of New Jersey. He graduated from the University of Pennsylvania at Philadelphia with an A.B. degree in 1792 then worked as an instructor at the university from 1792 to 1794. He studied medicine and practised in Dublin, Pennsylvania, and later in Greenwich, New Jersey. Moore spent several years in trading to the East Indies. He returned to Bucks County, Pennsylvania, and in 1808 purchased and operated grist and oil mills at , (now ) near Doylestown. He later erected and operated a sawmill and woollen factory.