Santolo Cirillo (active first half of 18th century, died 1742) was an Italian painter, engraver, and stucco artist, active in Naples. He was born in Grumo Nevano, a town near Naples. He contributed frescoes and paintings for Santa Caterina a Formiello, the Cathedral of San Gennaro, the Basilica of Santa Restituta, and Santa Donna Regina Nuova in Naples. He also painted for the Basilica di San Tammaro in his home town of Grumo Nevano.