Selepressin
Selepressin (INN) (code name FE-202158), also known as [Phe(2),Ile(3), (4),Orn(iPr)(8)]vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which was under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock. The Phase 2b/3 adaptive trial (SEPSIS-ACT) was terminated in February 2018 for futility. The trial was halted prior to the initiation of the arm for the highest dosing regimen of 5.0 ng/kg/min.
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Selepressin
Selepressin (INN) (code name FE-202158), also known as [Phe(2),Ile(3), (4),Orn(iPr)(8)]vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which was under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock. The Phase 2b/3 adaptive trial (SEPSIS-ACT) was terminated in February 2018 for futility. The trial was halted prior to the initiation of the arm for the highest dosing regimen of 5.0 ng/kg/min.
has abstract
Selepressin (INN) (code name F ...... sing regimen of 5.0 ng/kg/min.
@en
CAS number
876296-47-8
ChEMBL
FDA UNII code
8P2T76M0SJ
PubChem
Wikipage page ID
44,916,843
page length (characters) of wiki page
Wikipage revision ID
984,416,204
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ATC prefix
None
@en
CAS number
ChEMBL
ChemSpiderID
26,609,297
IUPAC name
PubChem
53,330,936
SMILES
CC[C@H][C@H]1CN[C@H]CCCCN
@en
StdInChIKey
JCVQBJTWWDYUFQ-MRUTUVJXSA-N
@en
synonyms
H-Cys-Phe-Ile-hGln-Asn-Cys-Pro-Orn-Gly-NH2
@en
wikiPageUsesTemplate
comment
Selepressin (INN) (code name F ...... sing regimen of 5.0 ng/kg/min.
@en
label
Selepressin
@en