The siege of Zaltbommel was a campaign that took place during the Eighty Years' War and the Anglo–Spanish War from May 15 to July 22, 1599. The Spanish led by Francisco López de Mendoza y Mendoza launched an offensive campaign around Bommelerwaard, which was defended by an Anglo-Dutch force under the command of Maurice of Orange. A siege on the town of Zaltbommel by Spanish troops was attempted but they had to lift the siege and were defeated in subsequent attempts to regain the initiative. Mendoza retreated and the Spanish army then found itself in chaos: mutinies took effect and as a result further operations were suspended for a number of years. As a result, the Dutch and English followed with a counter-offensive in the Spanish Netherlands.