Single-cell analysis
In the field of cellular biology, single-cell analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level. Due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, analyzing a single cell makes it possible to discover mechanisms not seen when studying a bulk population of cells. Technologies such as fluorescence-activated cell sorting (FACS) allow the precise isolation of selected single cells from complex samples, while high throughput single cell partitioning technologies, enable the simultaneous molecular analysis of hundreds or thousands of single unsorted cells; this is particularly useful for the analysis of transcriptome variation in genotypically identical cells, allowing the definition o
ATAC-seqAzim SuraniBio-MEMSChristopher Barner-KowollikCédric BlanpainDigital polymerase chain reactionGerman Network for Bioinformatics InfrastructureGraph theoryHuman somatic variationInduced stem cellsLaser-induced fluorescenceMAMSMass spectrometryMatthias LütolfMicro-Arrays for Mass SpectrometryMicro-arrays for mass spectrometryMultiomicsMuzlifah HaniffaPaweł UrbanRenato ZenobiSingle-Cell AnalysisSingle-cell analysisSingle-cell transcriptomicsSingle-cell variabilitySingle cell analysisSingle cell sequencing
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Single-cell analysis
In the field of cellular biology, single-cell analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level. Due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, analyzing a single cell makes it possible to discover mechanisms not seen when studying a bulk population of cells. Technologies such as fluorescence-activated cell sorting (FACS) allow the precise isolation of selected single cells from complex samples, while high throughput single cell partitioning technologies, enable the simultaneous molecular analysis of hundreds or thousands of single unsorted cells; this is particularly useful for the analysis of transcriptome variation in genotypically identical cells, allowing the definition o
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In the field of cellular biolo ...... used for analysis of tissues.
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In the field of cellular biolo ...... lls, allowing the definition o
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Single-cell analysis
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