Sodium-glucose transport proteins
Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose passes into the urine (glucosuria) because SGLT are saturated with the filtered glucose.
Active transportChemogenomicsCotransporterDapagliflozinDiscovery and development of gliflozinsEnterocyteIon transporterList of MeSH codes (D12.776.157)List of MeSH codes (D12.776.543)Na+/glucose symporterNa-glucose cotransporterOral rehydration therapyProstaglandin EP1 receptorProximal tubuleRemogliflozin etabonateRenal glycosuriaRenal physiologyRenal sodium reabsorptionRobert K. CraneRotaviral gastroenteritisRotavirusSGK1SGLTSergliflozin etabonateSleeve gastrectomySodium-glucose cotransporterSodium-glucose transport proteinSodium-glucose transporterSodium-glucose transportersSodium/glucose cotransporter 1Sodium/glucose cotransporter 2Sodium/glucose transporterSodium glucose cotransporterSodium glucose cotransporter 2Solute carrier familyStp4SymporterTofogliflozinUrotensin-II
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Sodium-glucose transport proteins
Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose passes into the urine (glucosuria) because SGLT are saturated with the filtered glucose.
has abstract
Kotransporter glukosa bergantu ...... an ulang glukosa dalam ginjal.
@in
Las proteínas de transporte so ...... s en el riñón (SGLT1 y SGLT2).
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Les cotransporteurs glucose so ...... un cas sécrété par le néphron.
@fr
Sodium-dependent glucose cotra ...... ted with the filtered glucose.
@en
鈉依賴型葡萄糖共同運輸蛋白(Sodium-dependent ...... 管會藉由本蛋白將濾液中的葡萄糖完全再吸收(近曲小管98%)。
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EntrezGene
HGNCid
OMIM id
RefSeq
Symbol
UniProt
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
997,484,907
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AltSymbols
SGLT1
@en
SGLT2
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SGLT3, SAAT1, DJ90G24.4
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Arm
p
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q
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band
EntrezGene
HGNCid
name
solute carrier family 5 , member 1
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solute carrier family 5 , member 2
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solute carrier family 5 , member four
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RefSeq
NM_000343
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NM_003041
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NM_014227
@en
UniProt
P13866
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P31639
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Q9NY91
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wikiPageUsesTemplate
subject
hypernym
comment
Kotransporter glukosa bergantu ...... an ulang glukosa dalam ginjal.
@in
Las proteínas de transporte so ...... s en el riñón (SGLT1 y SGLT2).
@es
Les cotransporteurs glucose so ...... n'est en aucun cas sécrété par
@fr
Sodium-dependent glucose cotra ...... ted with the filtered glucose.
@en
鈉依賴型葡萄糖共同運輸蛋白(Sodium-dependent ...... 管會藉由本蛋白將濾液中的葡萄糖完全再吸收(近曲小管98%)。
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label
Protein transpor natrium-glukosa
@in
Proteínas de transporte sodio-glucosa
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Sodium-glucose transport proteins
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Transporteur sodium-glucose
@fr
鈉依賴型葡萄糖共同運輸蛋白
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sameAs
wasDerivedFrom
isPrimaryTopicOf
name
solute carrier family 5 (low affinity glucose cotransporter), member four
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solute carrier family 5 (sodium/glucose cotransporter), member 1
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solute carrier family 5 (sodium/glucose cotransporter), member 2
@en