"Something's Got a Hold on Me" is a song by American singer Etta James. The song was written by James, Leroy Kirkland and Pearl Woods, while production was handled by Leonard and Phil Chess. It was released in 1962 as the third single from her 1962 self-titled album as a 7" vinyl disc. Musically, "Something's Got a Hold on Me" is an R&B track with elements of soul, blues and gospel. Upon its release, the single was an R&B hit, peaking at number four on the Billboard Hot R&B Sides chart.