Spongy degeneration of the central nervous system
Spongy degeneration of the central nervous system, also known as Canavan’s disease (CD), Van Bogaert-Bertrand type or Aspartoacylase (AspA) deficiency, is a rare autosomal recessive neurodegenerative disorder. It belongs to a group of genetic disorders known as leukodystrophies, where the growth and maintenance of myelin sheath in the central nervous system (CNS) are impaired. There are three types of spongy degeneration: infantile, congenital and juvenile, with juvenile being the most severe type. Common symptoms in infants include lack of motor skills, weak muscle tone, and macrocephaly. It may also be accompanied by difficulties in feeding and swallowing, seizures and sleep disturbances. Affected children typically die before the age of 10, but life expectancy can vary.
Wikipage redirect
Link from a Wikipage to another Wikipage
Spongy degeneration of the central nervous system
Spongy degeneration of the central nervous system, also known as Canavan’s disease (CD), Van Bogaert-Bertrand type or Aspartoacylase (AspA) deficiency, is a rare autosomal recessive neurodegenerative disorder. It belongs to a group of genetic disorders known as leukodystrophies, where the growth and maintenance of myelin sheath in the central nervous system (CNS) are impaired. There are three types of spongy degeneration: infantile, congenital and juvenile, with juvenile being the most severe type. Common symptoms in infants include lack of motor skills, weak muscle tone, and macrocephaly. It may also be accompanied by difficulties in feeding and swallowing, seizures and sleep disturbances. Affected children typically die before the age of 10, but life expectancy can vary.
has abstract
Spongy degeneration of the cen ...... 000 amongst this ethnic group.
@en
Wikipage page ID
67,252,443
page length (characters) of wiki page
Wikipage revision ID
1,026,335,744
Link from a Wikipage to another Wikipage
caption
Magnetic resonance imaging sca ...... indicator of Canavan's disease
@en
causes
Genetic
@en
diagnosis
Neuroimaging, urine examination
@en
duration
Terminal
@en
medication
N/A
@en
name
Spongy Degeneration of the Central Nervous System
@en
onset
-1.57788E7
prevention
DNA analysis, prenatal analysis
@en
risks
Family history
@en
specialty
Neurology
@en
symptoms
Hypotonia, macrocephaly, loss ...... es in breathing and swallowing
@en
synonym
Canavan's disease, Van Bogaert-Bertrand type, Aspartoacylase deficiency
@en
treatment
Palliative measures only
@en
types
Infantile, congenital, juvenile
@en
wikiPageUsesTemplate
comment
Spongy degeneration of the cen ...... but life expectancy can vary.
@en
label
Spongy degeneration of the central nervous system
@en