Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production. SAAs lower concentrations of testosterone through simulation of the negative feedback inhibition of the hypothalamus. SAAs are used in the treatment of androgen-dependent conditions in men and women, and are also used in veterinary medicine for the same purpose. They are the converse of nonsteroidal antiandrogens (NSAAs), which are antiandrogens that are not steroids and are structurally unrelated to testosterone.
SAAsSteroid anti-androgenSteroid anti-androgensSteroid antiandrogenSteroid antiandrogensSteroidal Anti-androgenSteroidal Anti-androgensSteroidal AntiandrogenSteroidal AntiandrogensSteroidal androgen receptor antagonistSteroidal androgen receptor antagonistsSteroidal anti-androgenSteroidal anti-androgensSteroidal antiandrogens
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11α-Hydroxyprogesterone15β-Hydroxycyproterone acetate5α-Dihydroethisterone9,11-Dehydrocortexolone 17α-butyrateAllyltestosterone1,2-dimethoxyethaanAntiandrogenBOMTBenorteroneBicalutamideBuserelinChlormadinone_acetateClascoteroneClometeroneComparison of bicalutamide with other antiandrogensCyproteroneCyproterone_acetateDelanteroneDelmadinone acetateDienogestDrospirenoneEM-5854EdogestroneFeminizing hormone therapyFlutamideGaleteroneInocoterone acetateList of antiandrogensList of steroidal antiandrogensList of steroidsMedical uses of bicalutamideMedroxyprogesterone_acetateMegestrol acetateMetogestNomegestrol_acetateNonsteroidal antiandrogenOsaterone acetateOxendolonePharmacodynamics of spironolactonePharmacology of bicalutamide
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Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production. SAAs lower concentrations of testosterone through simulation of the negative feedback inhibition of the hypothalamus. SAAs are used in the treatment of androgen-dependent conditions in men and women, and are also used in veterinary medicine for the same purpose. They are the converse of nonsteroidal antiandrogens (NSAAs), which are antiandrogens that are not steroids and are structurally unrelated to testosterone.
has abstract
A steroidal antiandrogen (SAA) ...... lly unrelated to testosterone.
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51,495,665
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1,021,934,657
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ATC prefix
G03HA
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Biological target
caption
Cyproterone acetate, the most widely employed steroidal antiandrogen.
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Chemical class
Steroidal
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synonyms
Steroidal androgen receptor antagonists
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Use
Prostate cancer; Benign prosta ...... e precocious puberty; Priapism
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subject
comment
A steroidal antiandrogen (SAA) ...... lly unrelated to testosterone.
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label
Steroidal antiandrogen
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