The women's 4 × 100 metre medley relay event at the 2008 Olympic Games took place on 15 and 17 August at the Beijing National Aquatics Center in Beijing, China. Dominating the race from the start, the Aussie women's relay team solidified their triumph to destroy the world record and to defend the Olympic title over their American rivals for the second straight time. The foursome of Emily Seebohm (59.33), Leisel Jones (1:04.58), Jessicah Schipper (56.25), and Lisbeth Trickett (52.53) put together a perfect ending with a blazing fast time of 3:52.69 to shave three seconds off their standard from the 2007 FINA World Championships in Melbourne.