Systematic evolution of ligands by exponential enrichment
Systematic evolution of ligands by exponential enrichment (SELEX), also referred to as in vitro selection or in vitro evolution, is a combinatorial chemistry technique in molecular biology for producing oligonucleotides of either single-stranded DNA or RNA that specifically bind to a target ligand or ligands. These single-stranded DNA or RNA are commonly referred to as aptamers. Although SELEX has emerged as the most commonly used name for the procedure, some researchers have referred to it as SAAB (selected and amplified binding site) and CASTing (cyclic amplification and selection of targets) SELEX was first introduced in 1990. In 2015 a special issue was published in the Journal of Molecular Evolution in the honor of quarter century of the SELEX discovery.
Anti-thrombin aptamersAptamerBacterial one-hybrid systemCUGBP1CUT&RUN sequencingCUT&Tag sequencingChIL-sequencingChIP sequencingCross-linking immunoprecipitationDNADeoxyribozymeDigital polymerase chain reactionElectrochemical aptamer-based biosensorsGerald JoyceHalal Development CorporationHistory of RNA biologyL-Ribonucleic acid aptamerLigase ribozymeNon-coding RNARNA therapeuticsRibozymeSELEXSELEX: Systematic Evolution of Ligands by Exponential EnrichmentSMiLE-SeqSpinach aptamerSystematic Evolution of Ligands by Exponential EnrichmentTan WeihongTwister ribozyme
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Systematic evolution of ligands by exponential enrichment
Systematic evolution of ligands by exponential enrichment (SELEX), also referred to as in vitro selection or in vitro evolution, is a combinatorial chemistry technique in molecular biology for producing oligonucleotides of either single-stranded DNA or RNA that specifically bind to a target ligand or ligands. These single-stranded DNA or RNA are commonly referred to as aptamers. Although SELEX has emerged as the most commonly used name for the procedure, some researchers have referred to it as SAAB (selected and amplified binding site) and CASTing (cyclic amplification and selection of targets) SELEX was first introduced in 1990. In 2015 a special issue was published in the Journal of Molecular Evolution in the honor of quarter century of the SELEX discovery.
has abstract
Evolução Sistemática de Ligant ...... feitos clínicos significantes.
@pt
La méthode Systematic Evolutio ...... isée aux oligonucléotides ADN.
@fr
SELEX是一種分子生物學試驗,用来找出和配體最親和的核酸序 ...... 應複製数百萬倍,再選擇多次,和配體最親和既核酸序列就會產生。
@zh
Systematic evolution of ligand ...... otentially improved stability.
@en
Системати́ческая эволю́ция лиг ...... акже повышать их стабильность.
@ru
التطور المنظومي للربائط بواسطة ...... سبة مرور ربع قرن على الاكتشاف.
@ar
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Evolução Sistemática de Ligant ...... mplificação cíclica de alvos).
@pt
La méthode Systematic Evolutio ...... isée aux oligonucléotides ADN.
@fr
SELEX是一種分子生物學試驗,用来找出和配體最親和的核酸序 ...... 應複製数百萬倍,再選擇多次,和配體最親和既核酸序列就會產生。
@zh
Systematic evolution of ligand ...... entury of the SELEX discovery.
@en
Системати́ческая эволю́ция лиг ...... ный выпуск в связи с 25-летием
@ru
التطور المنظومي للربائط بواسطة ...... سبة مرور ربع قرن على الاكتشاف.
@ar
label
Evolução Sistemática de Ligantes por Enriquecimento Exponencial
@pt
SELEX
@de
SELEX
@zh
Systematic evolution of ligands by exponential enrichment
@en
Évolution systématique de ligands par enrichissement exponentiel
@fr
Систематическая эволюция лигандов экспоненциальным обогащением
@ru
تطور منظومي للربائط بواسطة الاغناء المطرد
@ar