Thérèse Raquin is an American opera in two acts composed by Tobias Picker to a libretto by Gene Scheer based on the 1867 novel Thérèse Raquin by Émile Zola. It is Picker's third opera, following Emmeline (1996) and Fantastic Mr. Fox (1998). It was commissioned by the Dallas Opera, San Diego Opera, and the Opéra de Montréal. It premiered in November 2001. In 2006, a version with reduced orchestration was commissioned by Opera Theatre Europe; it premiered that year at the Royal Opera House and had its first New York performance in 2007 at Dicapo Opera Theatre. This version was subsequently produced by Boston University Opera Institute in 2009, Pittsburgh's Microscopic Opera Company in 2013, and both Long Beach Opera and the Chicago Opera Theater in 2015.