Thalassocnus is an extinct genus of semiaquatic ground sloths from the Miocene and Pliocene of the Pacific South American coast. It is monotypic within the subfamily Thalassocninae. The five species—T. antiquus, T. natans, T. littoralis, T. carolomartini, and T. yuacensis—represent a chronospecies, a population gradually adapting to marine life in one direct lineage. They are the only known aquatic sloths. They have been found in the Pisco Formation of Peru and the Bahía Inglesa, Coquimbo, and formations of Chile. Thalassocninae has been placed in both the families Megatheriidae and Nothrotheriidae.