Thioredoxin reductase
Thioredoxin reductases (TR, TrxR) (EC 1.8.1.9) are the only known enzymes to reduce thioredoxin (Trx). Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. In bacteria TrxR also catalyzes the reduction of glutaredoxin like proteins known as NrdH. Both classes are flavoproteins which function as homodimers. Each monomer contains a FAD prosthetic group, a NADPH binding domain, and an active site containing a redox-active disulfide bond.
AntioxidantArne HolmgrenAuranofinCatalytic triadDisulfide oxidoreductase DEC 1.8.1.9Ferredoxin-thioredoxin reductaseFerredoxin—NADP(+) reductaseGLRX2GSTK1GlutaredoxinLipoic acidList of EC numbers (EC 1)List of MeSH codes (D08)List of MeSH codes (D12.776)List of enzymesMartha L. LudwigMercury poisoningMethaneseleninic acidMotexafin gadoliniumNAD+ kinaseNFE2L2Oxidative foldingPhosphogluconate dehydrogenase (decarboxylating)Potassium arseniteRAPTAReductaseRibonucleotideSNARE (protein)Schistosoma mansoniSeleniumSelenium in biologySelenocysteineSelenolSelenoproteinTXN2TXNRD1TetanospasminThiol oxidoreductase1,2-dimethoxyethaan
Link from a Wikipage to another Wikipage
primaryTopic
Thioredoxin reductase
Thioredoxin reductases (TR, TrxR) (EC 1.8.1.9) are the only known enzymes to reduce thioredoxin (Trx). Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. In bacteria TrxR also catalyzes the reduction of glutaredoxin like proteins known as NrdH. Both classes are flavoproteins which function as homodimers. Each monomer contains a FAD prosthetic group, a NADPH binding domain, and an active site containing a redox-active disulfide bond.
has abstract
La tioredossina-disolfuro redu ...... ima è una flavoproteina (FAD).
@it
La tiorredoxina reductasa (TR, ...... ctrones para la reducción de .
@es
Les thiorédoxine réductases so ...... la recherche contre le cancer.
@fr
Thioredoxin reductases (TR, Tr ...... a redox-active disulfide bond.
@en
مختزلة الثيوريدوكسين هي إنزيم ...... يحوي على رابطة ثنائي كبريتيد.
@ar
チオレドキシンジスルフィドレダクターゼ(thioredoxi ...... thioredoxin oxidoreductaseがある。
@ja
硫氧还蛋白还原酶(英語:thioredoxin reduct ...... 前在癌症研究中亦作为重要的抗癌靶点,受到广泛关注和深入研究。
@zh
band
chromosome
EC number
EntrezGene
HGNCid
locus supplementary data
OMIM id
RefSeq
Symbol
UniProt
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
1,022,542,867
Link from a Wikipage to another Wikipage
Arm
p
@en
q
@en
band
Chromosome
ECnumber
EntrezGene
HGNCid
InterPro
IPR005982
@en
LocusSupplementaryData
-q13.33
@en
-q24.1
@en
name
thioredoxin reductase 1
@en
thioredoxin reductase 2
@en
thioredoxin reductase 3
@en
OMIM
PROSITE
PS00573
@en
RefSeq
NM_003330
@en
NM_006440
@en
XM_051264
@en
symbol
UniProt
Q16881
@en
Q86VQ6
@en
Q9NNW7
@en
wikiPageUsesTemplate
subject
comment
La tioredossina-disolfuro redu ...... ima è una flavoproteina (FAD).
@it
La tiorredoxina reductasa (TR, ...... ctrones para la reducción de .
@es
Les thiorédoxine réductases so ...... 2 + Thiorédoxine réductase-S2.
@fr
Thioredoxin reductases (TR, Tr ...... a redox-active disulfide bond.
@en
مختزلة الثيوريدوكسين هي إنزيم ...... يحوي على رابطة ثنائي كبريتيد.
@ar
チオレドキシンジスルフィドレダクターゼ(thioredoxi ...... thioredoxin oxidoreductaseがある。
@ja
硫氧还蛋白还原酶(英語:thioredoxin reduct ...... 前在癌症研究中亦作为重要的抗癌靶点,受到广泛关注和深入研究。
@zh
label
Thioredoxin reductase
@en
Thiorédoxine réductase
@fr
Tioredossina-disolfuro reduttasi
@it
Tiorredoxina reductasa
@es
مختزلة الثيوريدوكسين
@ar
チオレドキシンジスルフィドレダクターゼ
@ja
硫氧还蛋白还原酶
@zh
sameAs
wasDerivedFrom
isPrimaryTopicOf
name
thioredoxin reductase 1
@en
thioredoxin reductase 2
@en
thioredoxin reductase 3
@en