Thorowgood Smith (1744 in Accomac County, Virginia – August 13, 1810) was the second mayor of Baltimore from 1804 to 1808. He was appointed to that position when his predecessor James Calhoun resigned. He served for 4 years. He reformed the police system, and ordered the building the plumbing system by the Baltimore water company. Smith was well respected throughout the region. He died in 1810.