Tofenacin
Tofenacin is an antidepressant drug with a tricyclic-like structure which was developed and marketed in the United Kingdom and Italy in 1971 and 1981, respectively, by Brocades-Stheeman & Pharmacia (now part of Astellas Pharma). It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.
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Tofenacin
Tofenacin is an antidepressant drug with a tricyclic-like structure which was developed and marketed in the United Kingdom and Italy in 1971 and 1981, respectively, by Brocades-Stheeman & Pharmacia (now part of Astellas Pharma). It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.
has abstract
Tofenacin is an antidepressant ...... Parkinson's disease patients.
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Tofenacina é um medicamento an ...... entes com doença de Parkinson.
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alternative name
Elamol, Tofacine, Tofalin
@en
CAS number
10488-36-5 (HCl)
15301-93-6
FDA UNII code
C4A112M10H
PubChem
Wikipage page ID
35,874,626
page length (characters) of wiki page
Wikipage revision ID
998,972,128
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ATC prefix
None
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CAS number
CAS supplemental
ChemSpiderID
IUPAC name
N-methyl-2-[methoxy]ethanamine
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legal status
Rx-only
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PubChem
routes of administration
SMILES
OCc2ccccc2C
@en
StdInChIKey
PNYKGCPSFKLFKA-UHFFFAOYSA-N
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title
titlestyle
background:#ccccff
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tradename
Elamol, Tofacine, Tofalin
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UNII
C4A112M10H
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USAN
tofenacin hydrochloride
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wikiPageUsesTemplate
subject
hypernym
comment
Tofenacin is an antidepressant ...... Parkinson's disease patients.
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Tofenacina é um medicamento an ...... entes com doença de Parkinson.
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label
Tofenacin
@en
Tofenacina
@pt