Trace amine-associated receptor
Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that were discovered in 2001. TAAR1, the first of six functional human TAARs, has gained considerable interest in academic and proprietary pharmaceutical research due to its role as the endogenous receptor for the trace amines phenylethylamine, tyramine, and tryptamine – metabolic derivatives of the amino acids phenylalanine, tyrosine and tryptophan, respectively – ephedrine, as well as the synthetic psychostimulants, amphetamine, methamphetamine and methylenedioxymethamphetamine (MDMA, ecstasy). In 2004, it was shown that mammalian TAAR1 is also a receptor for thyronamines, decarboxylated and deiodinated relatives of thyroid hormones. TAAR2–TAA
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3-IodothyronamineCadaverineCopulation (zoology)1,2-dimethoxyethaanHTAARHordenineHuman trace amine-associated receptorHuman trace amine-associated receptorsList of acronyms: TMonoamine receptorN,N-DimethylethylamineNeuroimmune systemNeurotransmitterOctopamineOlfactory receptorPheromoneRhodopsin-like receptorsStephen LiberlesTAARTAAR-1TAAR-2TAAR-3TAAR-4TAAR-5TAAR-6TAAR-7TAAR1TAAR2TAAR3TAAR4TAAR5TAAR6TAAR7TAAR8TAAR9Taar (disambiguation)Thyroid hormonesThyronamineTrace Amine-Associated Receptor
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Trace amine-associated receptor
Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that were discovered in 2001. TAAR1, the first of six functional human TAARs, has gained considerable interest in academic and proprietary pharmaceutical research due to its role as the endogenous receptor for the trace amines phenylethylamine, tyramine, and tryptamine – metabolic derivatives of the amino acids phenylalanine, tyrosine and tryptophan, respectively – ephedrine, as well as the synthetic psychostimulants, amphetamine, methamphetamine and methylenedioxymethamphetamine (MDMA, ecstasy). In 2004, it was shown that mammalian TAAR1 is also a receptor for thyronamines, decarboxylated and deiodinated relatives of thyroid hormones. TAAR2–TAA
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Trace amine-associated recepto ...... amine odorants in vertebrates.
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March 2018
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Trace amine-associated recepto ...... of thyroid hormones. TAAR2–TAA
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Trace amine-associated receptor
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