USS Henry Andrew (1847) was a steamer acquired by the Union Navy during the American Civil War. She was used by the Navy to patrol navigable waterways of the Confederacy to prevent the South from trading with other countries. Henry Andrew was originally built in 1847 at New York City as a sailing brig, and converted to steam in 1859. She was purchased from her owner, Mr. Van Santvoord, at New York on 10 September 1861. Her first commanding officer was Acting Master Samuel Webb Mather.