The Ume River (Swedish: Ume älv or Umeälven) is one of the main rivers in northern Sweden. It is around 460 km (290 mi) long, and flows in a south-eastern direction from its source, the lake Överuman by the Norwegian border within the Scandinavian mountain range. For large parts, the European route E12, also known as Blå Vägen (Blue Route), follows its path. It passes through Vindelfjällen Nature Reserve and and drains into the Gulf of Bothnia on Sweden's east coast at the small town of Holmsund, and adjacent to the city of Umeå. Its chief tributary is the Vindel River.