WFXZ may refer to: * WFXZ-CD, a television station (channel 24 virtual/19 digital) licensed to Boston, Massachusetts, United States which has held the WFXZ call sign since 2003 * WBUF, a radio station (92.9 FM) licensed to Buffalo, New York, United States, which held the call sign WFXZ from 1980 to 1981 * WNTB, a radio station (92.3 FM) licensed to Topsail Beach, North Carolina, United States, which held the call sign WFXZ from 2000 to 2003 * WLUN, a radio station (100.9 FM) licensed to Pinconning, Michigan, United States, which held the call sign WFXZ from 1983 to 1984 * WPXU-TV, a television station (channel 34) licensed to Boston, Massachusetts, United States, which held the call sign WFXZ in 1999 * WQSL, a radio station (92.3 FM) licensed to Jacksonville, North Carolina, United