Wu Mingche (吳明徹) (512–578), courtesy name Tongzhao (通昭), was a general of the Chinese dynasty Chen Dynasty. He first served under the dynasty's founder Emperor Wu, but became the most prominent general of the state during the reign of Emperor Wu's nephew Emperor Xuan, successfully commanding the Chen army in seizing the region between the Yangtze River and the Huai River from rival Northern Qi. After Northern Qi was destroyed by Northern Zhou, however, Wu was defeated and captured by the Northern Zhou general Wang Gui (王軌). After he was taken to the Northern Zhou capital Chang'an, he died in anger.