Yttrium (90Y) clivatuzumab tetraxetan
Yttrium (90Y) clivatuzumab tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody-drug conjugate designed for the treatment of pancreatic cancer. The antibody part, clivatuzumab (targeted at MUC1), is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells. The drug was developed by Immunomedics, Inc. In March 2016 the phase III PANCRIT-1 trial in metastatic pancreatic cancer was terminated early due to lack of improvement of overall survival.
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Yttrium (90Y) clivatuzumab tetraxetan
Yttrium (90Y) clivatuzumab tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody-drug conjugate designed for the treatment of pancreatic cancer. The antibody part, clivatuzumab (targeted at MUC1), is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells. The drug was developed by Immunomedics, Inc. In March 2016 the phase III PANCRIT-1 trial in metastatic pancreatic cancer was terminated early due to lack of improvement of overall survival.
has abstract
Yttrium (90Y) clivatuzumab tet ...... provement of overall survival.
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إتريوم (90إ) كليفاتوزوماب تترا ...... تجاري هبام4-سايد (hPAM4-Cide).
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CAS number
943976-23-6
FDA UNII code
2L271110ED
Wikipage page ID
33,058,043
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Wikipage revision ID
1,003,788,856
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none
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CAS number
ChemSpiderID
none
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drug name
Yttrium clivatuzumab tetraxetan
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mab type
mab
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source
zu/o
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target
type
mab
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Verifiedfields
changed
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verifiedrevid
470,634,923
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changed
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wikiPageUsesTemplate
subject
hypernym
comment
Yttrium (90Y) clivatuzumab tet ...... provement of overall survival.
@en
إتريوم (90إ) كليفاتوزوماب تترا ...... تجاري هبام4-سايد (hPAM4-Cide).
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label
Yttrium (90Y) clivatuzumab tetraxetan
@en
إتريوم (90إ) كليفاتوزوماب تتراكسيتان
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isPrimaryTopicOf
name
Yttrium (90Y) clivatuzumab tetraxetan
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