about
P688
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signalingEssential role for ZAP-70 in both positive and negative selection of thymocytesInterchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular functionCharacterization of Lnk. An adaptor protein expressed in lymphocytesSubcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligasesLck availability during thymic selection determines the recognition specificity of the T cell repertoireInteractions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motifDifferential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinasesDlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsEphB6-null mutation results in compromised T cell functionAssociation of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytesRhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte developmentThe Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signalingRegulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2Regulation of T cell development by the deubiquitinating enzyme CYLDA spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte developmentQuantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub
P921
Q24312978-6E1FFD53-9061-4984-A65E-8361EAA38953Q24321424-B2F517FD-61C5-4DB1-8894-60E641CA7795Q24338926-7AEB16EC-5204-4C64-AB2A-C7C49BBDAACBQ28239518-DF8EDA4D-97B4-4AE2-B8F0-D67F986E3D59Q28240495-0F0D1881-DC5C-4FC2-84CA-82BA166B6F32Q28298459-0BB84911-523E-43A6-A5D9-C27548631647Q28507195-B5EB6DC6-1169-491B-8193-0E931BB9BD6AQ28507413-517E9304-DC18-48CD-B565-13A69408CF0AQ28511680-B93469C6-6CBC-48B5-B107-BD16911C39C8Q28513533-4D2D7643-F234-467A-B79D-4D86EA26AF48Q28585310-7DD02C34-9AF1-47FA-ADDD-98D002A4E750Q28585313-3D150657-26CF-491D-8992-8A8F640BEB4CQ28586244-9EE32084-97D0-488A-8451-1799E8384582Q28587191-2CA58C76-CDB5-47AC-9566-5B59BEC103C5Q28588773-9E0439EA-70D0-434F-8AE2-0689152FD634Q28589467-07EC79FA-1C8B-4350-B539-9652312E633FQ28771480-EB4BEFE4-EA3F-49B5-9ABA-8503267A5200
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Zeta-chain (TCR) associated protein kinase
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Zeta-chain (TCR) associated protein kinase
@en
Zeta-chain
@nl
type
label
Zeta-chain (TCR) associated protein kinase
@en
Zeta-chain
@nl
altLabel
70 kDa zeta-chain associated protein
@en
Zap70
@en
syk-related tyrosine kinase
@en
tyrosine-protein kinase ZAP-70
@en
prefLabel
Zeta-chain (TCR) associated protein kinase
@en
Zeta-chain
@nl
P361
P527
P637
P680
P681
P682
P352
P31
P352
P361
P527
P637
NP_001276541
NP_001276694
NP_001276695
XP_006495959
P680
P681
P682
P702
P703
P705
ENSMUSP00000027291
ENSMUSP00000139990