about
P688
53BP2S, interacting with insulin receptor substrates, modulates insulin signalingImpaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistanceThe density of extracellular matrix proteins regulates inflammation and insulin signaling in adipocytesThe TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteinsYAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationDouble-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisDevelopment of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic diseaseGrowth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytesIntracellular redistribution of nuclear and nucleolar proteins during differentiation of 32D murine hemopoietic cellsSubcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null miceCrosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud developmentInsulin signaling and glucose homeostasis in mice lacking protein tyrosine phosphatase alphaTumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytesOverexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistanceA novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes.Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis
P921
Q24298847-125F0F17-BC29-492A-AD5F-B1BA8F898580Q28505114-22C361FA-5F7A-48C2-8458-2CEF3219D670Q28505719-C86CBBF1-AF44-4EE2-B9A0-FD2BDD25F1B4Q28507365-2D60CA40-7C53-464D-9C60-2501B870ECB7Q28507494-AB2ED5C9-3EE3-415E-8DD6-A7887F32D17FQ28510028-42DE2DEB-77DF-4A5B-966A-916645CF167EQ28510789-CAFBFA7E-CBE2-4BAE-8A03-F2CBD4DEF0E8Q28585724-6DE3A3A2-9B55-4BB0-8653-8A8A4C2C1CF8Q28585956-B4BBEF30-A5B8-4425-8E9B-9C4CF28CEDF0Q28587328-DAD50BF8-293F-4AF2-991E-466E9F285B31Q28587428-0EF76980-CFFB-49FF-AF6B-193E9188C649Q28592948-8B6D1853-6670-4A2E-BA4E-85D8B1184D2CQ35126720-44C220B7-AC9B-4FC1-A06E-0EA5A560FCBCQ36491374-D62C7BFE-E501-49C3-9306-0E18479A05E6Q39292601-55F53EDC-F5A0-41A6-AEB0-78E73893BB88Q41791619-6D175CF2-859E-4DAC-B511-C6B473E023F0Q85070847-02EBB815-9E86-4973-B5CD-708A77C28848
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Insulin receptor substrate 1
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Insulin receptor substrate 1
@en
type
label
Insulin receptor substrate 1
@en
altLabel
Irs1
@en
insulin receptor substrate 1
@en
uniprot:P35569
@en
prefLabel
Insulin receptor substrate 1
@en
P680
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ENSMUSP00000063795