P3781
FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl ratsFarnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trialThe response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid.Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis.Obeticholic acid and budesonide for the treatment of primary biliary cirrhosis.Obeticholic acid: expanding the therapeutic landscape of NASH.Obeticholic acid for the treatment of primary biliary cirrhosis.Obeticholic Acid: First Global Approval.Obeticholic acid for the treatment of primary biliary cholangitis.Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid.Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats.Bile acid receptor agonists INT747 and INT777 decrease oestrogen deficiency-related postmenopausal obesity and hepatic steatosis in mice.Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension.Effects of obeticholic acid on lipoprotein metabolism in healthy volunteers.The FXR agonist obeticholic acid prevents gut barrier dysfunction and bacterial translocation in cholestatic rats.Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndromeObeticholic acid for the treatment of fatty liver disease—NASH no more?Human Multilineage 3D Spheroids as a Model of Liver Steatosis and FibrosisPractical strategies for pruritus management in the obeticholic acid-treated patient with PBC: proceedings from the 2018 expert panelIdentification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptorThe Appropriate Timing and Dose of Obeticholic Acid in Patients With Primary Biliary CirrhosisTrials of obeticholic acid for non-alcoholic steatohepatitisTrials of obeticholic acid for non-alcoholic steatohepatitis - Authors' replyIs obeticholic Acid the solution to nonalcoholic steatohepatitis?Obeticholic acid and resveratrol in nonalcoholic fatty liver disease: all that is gold does not glitter, not all those who wander are lostObeticholic acid, a Farensoid-X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats
P921
Q27329677-577E184F-8F6F-4FF5-B432-1FF309F58821Q28253122-A5331D2B-8C28-4EEF-958C-00DEFC47CD88Q34444158-FD7E990E-80CE-4978-BB9C-997A7E3856AAQ34453425-637FA8DC-E8DD-47C8-9FF0-E78F63426454Q36598778-991376A0-710C-42D4-BE5A-31AF2B3EEEB6Q38175055-3C5DF850-02EB-44CD-A718-597F87D4B183Q38416407-84471190-3AE7-4ACF-B985-8E28DB43EB93Q38628470-EB9D55AE-5AEB-4DAB-957A-BF418EA6C668Q38894300-7FAFF4AB-A0A8-48E3-AD89-1D23E008C442Q38911238-21E2A45C-7590-4B0D-8C18-E869AB20B36AQ40060312-42D8E40B-10BC-46F5-B440-7F210FD2E475Q40848070-CD52CF57-91C6-475B-A3F6-BB0FDD0475EDQ51604898-B74193DA-C05B-438E-9C55-9B4820C9EC93Q51636207-B4E9BE37-DD45-40E7-B50D-E090C80C6B2BQ53615614-9E83D1F1-D315-435C-B43B-371C7B530FD5Q53643126-9D057B96-F158-425A-B98B-AA21F1385C9AQ57582289-EC2BC05A-7B16-4B47-B66D-CD139716DBAFQ59413679-59A2A8BA-167D-4DFF-84E7-E156CB83E695Q64085516-34489ABE-18BD-437E-9861-4CBAA42ECD64Q64230889-13C6F896-6FEE-4AD2-9728-C2B4D816F780Q64375311-B5ECCD0D-E67E-4CFE-83F5-E244110F08F8Q85514146-6E5D34F4-93F7-41C3-8F12-932DE4CF96F5Q85583991-EE7C91DA-B352-430B-8B58-3F984AD6E43FQ85583993-93D03EF5-AC12-4C78-8640-9EAB4FB6FF4EQ86846351-6C0CAD79-EEED-4DB6-822E-1294AEC158D8Q86892452-563E9CBF-602A-4593-BDE2-D66D60405D86Q87430870-8C89760D-F0B3-4391-9307-557EE4001D3D
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Axit obeticholic
@vi
acide obéticholique
@fr
acidum obeticholicum
@la
obeticholic acid
@en
obetikolsyre
@nn
ácido obeticólico
@es
ácido obeticólico
@pt
ácido obeticólico
@pt-br
обетихолевая кислота
@ru
حمض أسيتوم أوبيتيكوليك
@ar
label
Axit obeticholic
@vi
acide obéticholique
@fr
acidum obeticholicum
@la
obeticholic acid
@en
obetikolsyre
@nn
ácido obeticólico
@es
ácido obeticólico
@pt
ácido obeticólico
@pt-br
обетихолевая кислота
@ru
حمض أسيتوم أوبيتيكوليك
@ar
altLabel
6-ECDCA
@en
6-ECDCA
@nn
6-Et CDCA
@en
6-Ethyl-CDCA
@en
6-ethylchenodeoxycholic acid
@en
6-etylkenodeoksykolsyre
@nn
6alpha-Ethyl-chenodeoxycholic acid
@en
6α-ethylchenodeoxycholic acid
@en
INT-747
@en
OCA
@en
prefLabel
Axit obeticholic
@vi
acide obéticholique
@fr
acidum obeticholicum
@la
obeticholic acid
@en
obetikolsyre
@nn
ácido obeticólico
@es
ácido obeticólico
@pt
ácido obeticólico
@pt-br
обетихолевая кислота
@ru
حمض أسيتوم أوبيتيكوليك
@ar
P2175
P2275
P592
P6366
P661
P662
P665
P683
P2017
CC[C@@H]1[C@@H]2C[C@@H](CC[C@@ ...... C[C@@H]4[C@H](C)CCC(=O)O)C)C)O
P2067
P2115
N0000192568