P185
P26
Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotidesMetazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidanceProtein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signallingCVAK104 is a novel regulator of clathrin-mediated SNARE sorting.New insights into the maternal to zygotic transitionVisualisation and quantification of morphogen gradient formation in the zebrafishEvolution of Brachyury proteins: identification of a novel regulatory domain conserved within BilateriaTargeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fatesHighly variable penetrance of abnormal phenotypes in embryonic lethal knockout miceRab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in XenopusTitration of four replication factors is essential for the Xenopus laevis midblastula transitionMolecular components of the endoderm specification pathway in Xenopus tropicalis.Xnrs and activin regulate distinct genes during Xenopus development: activin regulates cell division.A screen for targets of the Xenopus T-box gene Xbra.Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selectionActive cell migration drives the unilateral movements of the anterior visceral endoderm.The Wnt/beta-catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signalling.Techniques and probes for the study of Xenopus tropicalis development.A mechanism for the sharp transition of morphogen gradient interpretation in XenopusA mechanism regulating the onset of Sox2 expression in the embryonic neural plate.Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data.T-box genes: what they do and how they do it.USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.no tail integrates two modes of mesoderm induction.SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.A divergent Tbx6-related gene and Tbx6 are both required for neural crest and intermediate mesoderm development in XenopusNew mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites.Xwnt11 and the regulation of gastrulation in Xenopus.T-targets: clues to understanding the functions of T-box proteins.Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling.Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists.Controlling morpholino experiments: don't stop making antisense.Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53Investigating physical chromatin associations across the Xenopus genome by chromatin immunoprecipitation.Genome-wide snapshot of chromatin regulators and states in Xenopus embryos by ChIP-Seq.The midblastula transition defines the onset of Y RNA-dependent DNA replication in Xenopus laevis.Zebrafish promoter microarrays identify actively transcribed embryonic genes.Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells.Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins.Xenopus genetics and genomics.
P50
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Deputy Chief Executive Officer ...... is Crick Institute, since 2015
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جيمس سميث
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