about
Poly(A)-specific ribonucleaseCCR4-NOT transcription complex subunit 1CCR4-NOT transcription complex subunit 6 likeCCR4-NOT transcription complex subunit 2CCR4-NOT transcription complex subunit 7CCR4-NOT transcription complex subunit 8Phosphodiesterase 12Poly(A) specific ribonuclease subunit PAN2Target of EGR1, exonucleasePARN like, ribonuclease domain containing 1Poly(A) specific ribonuclease subunit PAN3CCR4-NOT transcription complex subunit 8CCR4-NOT transcription complex subunit 6NocturninCCR4-NOT transcription complex, subunit 7CCR4-NOT transcription complex, subunit 1CCR4-NOT transcription complex, subunit 2CCR4-NOT transcription complex, subunit 6CCR4-NOT transcription complex, subunit 6-likeCCR4-NOT transcription complex, subunit 8PAN2 poly(A) specific ribonuclease subunitPhosphodiesterase 12Target of EGR1, member 1 (nuclear)PAN3 poly(A) specific ribonuclease subunitPoly(A)-specific ribonuclease (deadenylation nuclease)NocturninPAN2-PAN3 deadenylation complex catalytic subunit PAN2CCR4-NOT core exoribonuclease subunit CCR4 YAL021CCCR4-NOT core DEDD family RNase subunit POP2 YNR052CPan3p YKL025CPoly(A)-specific ribonuclease YGL094CRNA exonuclease YMR285C3'-5' poly(A) RNA exonuclease YML118WRNA exonuclease YOL042WPoly(A) specific ribonuclease subunit PAN2Phosphodiesterase 12CCR4-NOT transcription complex, subunit 6NocturninCCR4-NOT transcription complex, subunit 7CCR4-NOT transcription complex, subunit 6-like
P680
CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.Conservation of the deadenylase activity of proteins of the Caf1 family in humanIdentification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding proteinInteraction of antiproliferative protein Tob with the CCR4-NOT deadenylase complexCNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell deathThe role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability
P921
Q21100322-615C91B9-5783-4370-B695-058CB4F688CCQ21100322-A3623596-813B-40F7-B664-D31D6FDCD347Q21100322-C6AE1D8A-F8BB-4776-AF4E-423D4BA7B4C8Q21109861-60881713-E426-475E-84BC-3C4888442ABDQ21109871-1155A48A-A7A8-414F-B148-12F76C0911C7Q21109871-BE38AED9-723D-44A2-BFF6-CB8E0A357392Q21109876-54E1773C-7477-42FE-8C6B-4FCFA602E3B1Q21111282-389EE3DD-34C4-4C0E-80D4-0B0A0B9660B5Q21111282-C32F3254-0B62-4A34-B8E8-959C46B04FEBQ21112885-B12CA641-D842-46AE-BB28-2AD5F1949002Q21112885-C3AD01E6-BCE8-41C8-8F7E-8B4CDEB553B8Q21119697-A3F9EA33-291D-426C-A1C1-6BAB2009D22EQ21122470-75CE74B5-35F6-43D6-8F0A-E9A0AA330C01Q21122470-BA33A1B8-0E9E-49A9-A6C1-766E607BD45CQ21123197-CEB5AC05-DCDC-4D95-AA78-E82F55BA8F94Q21123287-4368283C-4725-4E35-9446-2856050D9DE7Q21123287-78D3D312-736D-486A-B1C0-109D2406607FQ21126791-205CEED5-8011-4FEB-932A-4B58EE892794Q21126791-A58FDFF4-798C-4FBB-8C29-AAD003A14223Q21141285-389AD78A-3237-48E5-85FC-B1891381CCCDQ21171707-0163B129-EFD6-40FB-B140-C8774703AD9CQ21171707-5C57CEC7-4276-4D69-A6BF-00058C5E2EEBQ21483218-2804AAF0-1341-4A1B-B7FB-D23B497D0723Q21483218-C647F8E9-BCD9-4437-B407-729EA05BA377Q21495442-7B147E33-AA07-4816-958A-C63244755ABDQ21495442-BD3F0E48-6481-4C42-8A9C-5FDAB17FD38EQ21499319-966759A5-DBCA-4CBB-9D1F-660C7AA0E186Q21499319-C84A7C89-676C-463B-AC08-88FDE90DBB48Q21499323-4D1B1CBB-2D01-4B7D-89B7-6D83394EB2F6Q21499329-40DA79A2-B14A-4CEB-8E76-844538BE0938Q21499329-4D8EA18A-B3FB-4A13-9773-0066B0AC4767Q21499331-47F325B4-7596-4E35-9E4E-FF5D101C1FE8Q21499331-EE57DBBC-4F58-49BD-9BB2-3683EBC6813EQ21499335-6105FCD3-A21A-4355-9F52-EC73865552CDQ21985958-86C7CF43-5058-4337-9253-3531B98C18FAQ21985965-D579E078-41BF-4B28-BBF9-0E7F42EB84FAQ21987005-33D0FD50-1DBE-44B0-9A95-01978D4BA42FQ21988395-90ABFBF6-2F6B-45BA-BB82-319C244FB8C6Q21989849-1006557C-7807-437C-9605-552E894DD1F4Q21989849-3517D24B-FEF1-482B-A89E-3D8BF72B3A80
P680
description
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
@en
moleculaire functie
@nl
name
poly(A)-specific ribonuclease activity
@en
type
label
poly(A)-specific ribonuclease activity
@en
altLabel
3'-exoribonuclease activity
@en
GO:0004535
@en
poly(A)-specific RNase activity
@en
prefLabel
poly(A)-specific ribonuclease activity
@en
P2888
P591
P686
GO:0004535