about
p(Y700;731;774)-CBL:CRK:RAPGEF1Active TrkA receptor:p-FRS2:CRKL:RAPGEF1PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3GHGF:p-4Y-MET:p-5Y-GAB1; HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK;CRKL:RAPGEF1CBL:CRKL binds RAPGEF1p-FRS2:CRKL binds C3Gp130Cas and C3G bind PDGFR bound CrkRAPGEF1 binds CRK;CRKLCRKL:RAPGEF1p-CRKL:RAPGEF1
P527
P688
nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteinsEpac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction controlRap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthStructural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
P921
Q50262943-F5F1A054-BF67-4287-A4C9-7BE315E2C056Q50271367-BD33FDEE-6701-4BC2-A57E-37C3509C26A6Q50271584-E6ED9923-9367-4957-8BB0-BEF7E0EDF036Q50272123-B6353384-C1C5-43E1-B92A-837D616DE2EEQ50292630-53AC86FA-D52A-4F56-9B59-3302B997F90CQ50297766-820644E7-F02C-4E1C-B8C6-CA5EBCBAF810Q50297855-B2CFD576-B0B3-43B3-85BA-68D589E1030FQ50298123-08A6A9E8-EEAB-4535-BDA2-9937C39427D1Q56856903-2CE9F3E9-8496-431A-83C4-8EB90C1EC09BQ56856906-4A7ECF2A-F3DF-4777-93BA-5C42F3DE4D7C
P527
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Rap guanine nucleotide exchange factor 1
@en
Rap guanine nucleotide exchange factor 1
@nl
type
label
Rap guanine nucleotide exchange factor 1
@en
Rap guanine nucleotide exchange factor 1
@nl
altLabel
CRK SH3-binding GNRP
@en
Guanine nucleotide-releasing factor 2
@en
Protein C3G
@en
RAPGEF1
@en
Rap guanine nucleotide exchange factor (GEF) 1
@en
guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
@en
rap guanine nucleotide exchange factor 1
@en
prefLabel
Rap guanine nucleotide exchange factor 1
@en
Rap guanine nucleotide exchange factor 1
@nl
P637
P680
P681
P682
P705
P352
P637
P31
P352
P637
NP_001291204
NP_001364864
NP_001364865
NP_001364866
NP_001364867
XP_005272243
XP_006717130
XP_006717135
P680
P681
P682
P702
P703
P705
ENSP00000361263
ENSP00000361264
ENSP00000361269
ENSP00000394296
ENSP00000407210
ENSP00000410640